Endocrine Abstracts

Introduction: Primary hyperparathyroidism (pHPT) is the most frequent cause of hypercalcemia in ambulatory patients. Most persons have no symptoms, and pHPT usually is diagnosed after an elevated serum calcium (Ca2+) level is found incidentally. Parathyroidectomy is the definitive treatment for pHPT. There have been several different approaches to the medical management of pHPT. Our aim in this study is to compare alendronate sodium (ALN) and raloxifene (RLX) effici...

Objective: Patients with hyperprolactinemia who require medical therapy are typically treated with dopamine agonists (DA). In most cases, medical therapy with DA normalizes the level of prolactin (PRL), restores gonadal function and fertility, and substantially reduces the size of the tumor. Here, we aimed to compare the efficacy of cabergoline (CAB) and bromocriptine (BRC) in hyperprolactinemic patients retrospectively.Methods: Retrospective analysis of...

Objective: Long acting somatostatin analogs commonly used as adjuvant treatment of acromegalic patients after noncurative surgery. We aimed to compare the efficacy of octreotide LAR (OCT) and lanreotide Autogel (LAN) in acromegalic patients.Methods: Sixty-eight patients that cure could not be achieved by transsfenoidal endoscopic or microscopic pituitary surgery between 2003 and 2009 were retrospectively analyzed (25 men and 43 women; mean age 41.1±...

Objective: Most of the papillary thyroid microcarcinomas (PTMC) are incidentally discovered in pathological examination after the surgery of benign thyroid disorders. The purpose of the present study was to evaluate clinicopathologic features of incidental and nonincidental PTMC.Material and methods: We evaluated 56 patients with PTMC between 2003 and 2008 at the Division of Endocrinology of the Numune Training and Research Hospital. We analyzed the tumo...

Objective: Thyroid malignancy detected incidentally in patients who underwent surgery for thyrotoxicosis has been reported at different rates. The aim of this study was to investigate the rate of incidental thyroid carcinoma (ITC) in thyrotoxic patients underwent surgery in our institution.Methods: The prevalence of ITC was investigated in patients who underwent surgery for Graves’ disease (GD), toxic adenoma (TA) or toxic multinodular goiter (TMNG)...

Objective: Hyperprolactinemia is the most common abnormality of the hypothalamic–pituitary axis. In the majority of patients with hyperprolactinemia monomeric prolactin (monoPRL) namely PRL with a molecular weight of 23 kDa predominates. But, in some patients with hyperprolactinemia high molecular weight forms of PRL namely macroprolactin (macroPRL) is detected. We aimed to investigate the clinic and radiologic features associated with the macroPRL....